AAV-mediated in vivo knockdown of luciferase using combinatorial RNAi and U1i

RNA interference (RNAi) has been successfully employed for specific inhibition of gene expression; however, safety and delivery of RNAi remain critical issues. We investigated the combinatorial use of RNAi and U1 interference (U1i). U1i is a gene-silencing technique that acts on the pre-mRNA by prev...

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Detalles Bibliográficos
Autores principales: Koornneef, A, van Logtenstein, R, Timmermans, E, Pisas, L, Blits, B, Abad, X, Fortes, P, Petry, H, Konstantinova, P, Ritsema, T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169806/
https://www.ncbi.nlm.nih.gov/pubmed/21472008
http://dx.doi.org/10.1038/gt.2011.41

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169806/
https://www.ncbi.nlm.nih.gov/pubmed/21472008
http://dx.doi.org/10.1038/gt.2011.41

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