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Conformational selection or induced fit? 50 years of debate resolved
Exactly 50 years ago, biochemists raised the question of the mechanism of the conformational change that mediates “allosteric” interactions between regulatory sites and biologically active sites in regulatory/receptor proteins. Do the different conformations involved already exist spontaneously in t...
Autores principales: | Changeux, Jean-Pierre, Edelstein, Stuart |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Faculty of 1000 Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169905/ https://www.ncbi.nlm.nih.gov/pubmed/21941598 http://dx.doi.org/10.3410/B3-19 |
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