Affinity of estrogens for human progesterone receptor A and B monomers and risk of breast cancer: a comparative molecular modeling study

BACKGROUND: The human progesterone receptor (hPR) belongs to the steroid receptor family. It may be found as monomers (A and B) and or as a dimer (AB). hPR is regarded as the prognostic biomarker for breast cancer. In a cellular dimer system, AB is the dominant species in most cases. However, when a...

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Detalles Bibliográficos
Autores principales: Hasan, Tarique N, B, Leena Grace, Masoodi, Tariq A, Shafi, Gowhar, Alshatwi, Ali A., Sivashanmugham, P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169952/
https://www.ncbi.nlm.nih.gov/pubmed/21918635
http://dx.doi.org/10.2147/AABC.S17371

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169952/
https://www.ncbi.nlm.nih.gov/pubmed/21918635
http://dx.doi.org/10.2147/AABC.S17371

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