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Cost–utility analysis of prophylaxis versus treatment on demand in severe hemophilia A
BACKGROUND: Individuals with severe hemophilia A have reduced blood levels of clotting factor VIII (FVIII) leading to recurrent bleeding into joints and muscles. Primary prophylaxis with clotting factor concentrates started early in childhood prevents joint bleeds, thus avoiding joint damage and imp...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169977/ https://www.ncbi.nlm.nih.gov/pubmed/21935333 http://dx.doi.org/10.2147/CEOR.S16670 |