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Cost–utility analysis of prophylaxis versus treatment on demand in severe hemophilia A

BACKGROUND: Individuals with severe hemophilia A have reduced blood levels of clotting factor VIII (FVIII) leading to recurrent bleeding into joints and muscles. Primary prophylaxis with clotting factor concentrates started early in childhood prevents joint bleeds, thus avoiding joint damage and imp...

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Detalles Bibliográficos
Autores principales: Colombo, Giorgio L, Di Matteo, Sergio, Mancuso, Maria Elisa, Santagostino, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3169977/
https://www.ncbi.nlm.nih.gov/pubmed/21935333
http://dx.doi.org/10.2147/CEOR.S16670