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A kinetic platform for in silico modeling of the metabolic dynamics in Escherichia coli

BACKGROUND: A prerequisite for a successful design and discovery of an antibacterial drug is the identification of essential targets as well as potent inhibitors that adversely affect the survival of bacteria. In order to understand how intracellular perturbations occur due to inhibition of essentia...

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Detalles Bibliográficos
Autores principales: Barve, Aditya, Gupta, Anvita, Solapure, Suresh M, Kumar, Ansu, Ramachandran, Vasanthi, Seshadri, Kothandaraman, Vali, Shireen, Datta, Santanu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170011/
https://www.ncbi.nlm.nih.gov/pubmed/21918631
http://dx.doi.org/10.2147/AABC.S14368