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Mutation Rates across Budding Yeast Chromosome VI Are Correlated with Replication Timing
Previous experimental studies suggest that the mutation rate is nonuniform across the yeast genome. To characterize this variation across the genome more precisely, we measured the mutation rate of the URA3 gene integrated at 43 different locations tiled across Chromosome VI. We show that mutation r...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170098/ https://www.ncbi.nlm.nih.gov/pubmed/21666225 http://dx.doi.org/10.1093/gbe/evr054 |