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Long-range diastereoselectivity in Ugi reactions of 2-substituted dihydrobenzoxazepines

The Ugi reaction of 2-substituted dihydrobenzoxazepines was found to proceed with unexpectedly good diastereoselectivitiy (diastereoisomeric ratios up to 9:1), despite the large distance between the pre-existing stereogenic centre and the newly generated one. This result represents the first good 1,...

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Detalles Bibliográficos
Autores principales: Banfi, Luca, Basso, Andrea, Cerulli, Valentina, Rocca, Valeria, Riva, Renata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170203/
https://www.ncbi.nlm.nih.gov/pubmed/21915196
http://dx.doi.org/10.3762/bjoc.7.109