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Increased complexity of Tmem16a/Anoctamin 1 transcript alternative splicing

BACKGROUND: TMEM16A (Anoctamin 1; ANO1) is an eight transmembrane protein that functions as a calcium-activated chloride channel. TMEM16A in human exhibits alternatively spliced exons (6b, 13 and 15), which confer important roles in the regulation of channel function. Mouse Tmem16a is reported to co...

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Detalles Bibliográficos
Autores principales: O'Driscoll, Kate E, Pipe, Rachel A, Britton, Fiona C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170211/
https://www.ncbi.nlm.nih.gov/pubmed/21824394
http://dx.doi.org/10.1186/1471-2199-12-35