Cellular prion protein protects from inflammatory and neuropathic pain

Cellular prion protein (PrP(C)) inhibits N-Methyl-D-Aspartate (NMDA) receptors. Since NMDA receptors play an important role in the transmission of pain signals in the dorsal horn of spinal cord, we thus wanted to determine if PrP(C )null mice show a reduced threshold for various pain behaviours. We...

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Detalles Bibliográficos
Autores principales: Gadotti, Vinicius M, Zamponi, Gerald W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170224/
https://www.ncbi.nlm.nih.gov/pubmed/21843375
http://dx.doi.org/10.1186/1744-8069-7-59

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170224/
https://www.ncbi.nlm.nih.gov/pubmed/21843375
http://dx.doi.org/10.1186/1744-8069-7-59

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