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Methyl salicylate 2-O-β-D-lactoside, a novel salicylic acid analogue, acts as an anti-inflammatory agent on microglia and astrocytes

BACKGROUND: Neuroinflammation has been known to play a critical role in the pathogenesis of Alzheimer's disease (AD). Activation of microglia and astrocytes is a characteristic of brain inflammation. Epidemiological studies have shown that long-term use of non-steroidal anti-inflammatory drugs...

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Detalles Bibliográficos
Autores principales: Lan, Xi, Liu, Rui, Sun, Lan, Zhang, Tiantai, Du, Guanhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170234/
https://www.ncbi.nlm.nih.gov/pubmed/21831328
http://dx.doi.org/10.1186/1742-2094-8-98