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Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus
Protease activated receptor-1 (PAR1) is expressed in multiple cell types in the CNS, with the most prominent expression in glial cells. PAR1 activation enhances excitatory synaptic transmission secondary to the release of glutamate from astrocytes following activation of astrocytically-expressed PAR...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170262/ https://www.ncbi.nlm.nih.gov/pubmed/21827709 http://dx.doi.org/10.1186/1756-6606-4-32 |