Activation of protease activated receptor 1 increases the excitability of the dentate granule neurons of hippocampus

Protease activated receptor-1 (PAR1) is expressed in multiple cell types in the CNS, with the most prominent expression in glial cells. PAR1 activation enhances excitatory synaptic transmission secondary to the release of glutamate from astrocytes following activation of astrocytically-expressed PAR...

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Detalles Bibliográficos
Autores principales: Han, Kyung-Seok, Mannaioni, Guido, Hamill, Cecily E, Lee, Jaekwang, Junge, Candice E, Lee, C Justin, Traynelis, Stephen F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170262/
https://www.ncbi.nlm.nih.gov/pubmed/21827709
http://dx.doi.org/10.1186/1756-6606-4-32

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