Role of inducible nitric oxide synthase pathway on methotrexate-induced intestinal mucositis in rodents

BACKGROUND: Methotrexate treatment has been associated to intestinal epithelial damage. Studies have suggested an important role of nitric oxide in such injury. The aim of this study was to investigate the role of nitric oxide (NO), specifically iNOS on the pathogenesis of methotrexate (MTX)-induced...

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Detalles Bibliográficos
Autores principales: Leitão, Renata FC, Brito, Gerly AC, Oriá, Reinaldo B, Braga-Neto, Manuel B, Bellaguarda, Emmanuelle AL, Silva, Johann V, Gomes, Antoniella S, Lima-Júnior, Roberto CP, Siqueira, Francisco JWS, Freire, Rosemeyre S, Vale, Mariana L, Ribeiro, Ronaldo A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170268/
https://www.ncbi.nlm.nih.gov/pubmed/21846355
http://dx.doi.org/10.1186/1471-230X-11-90

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170268/
https://www.ncbi.nlm.nih.gov/pubmed/21846355
http://dx.doi.org/10.1186/1471-230X-11-90

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