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Drug metabolizing enzyme activities versus genetic variances for drug of clinical pharmacogenomic relevance
Enzymes are critically important in the transportation, metabolism, and clearance of most therapeutic drugs used in clinical practice today. Many of these enzymes have significant genetic polymorphisms that affect the enzyme's rate kinetics. Regarding drug metabolism, specific polymorphisms to...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170273/ https://www.ncbi.nlm.nih.gov/pubmed/21906384 http://dx.doi.org/10.1186/1559-0275-8-12 |