The ADAMs family of proteases: new biomarkers and therapeutic targets for cancer?

The ADAMs are transmembrane proteins implicated in proteolysis and cell adhesion. Forty gene members of the family have been identified, of which 21 are believed to be functional in humans. As proteases, their main substrates are the ectodomains of other transmembrane proteins. These substrates incl...

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Detalles Bibliográficos
Autores principales: Duffy, Michael J, Mullooly, Maeve, O'Donovan, Norma, Sukor, Sumainizah, Crown, John, Pierce, Aisling, McGowan, Patricia M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170276/
https://www.ncbi.nlm.nih.gov/pubmed/21906355
http://dx.doi.org/10.1186/1559-0275-8-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170276/
https://www.ncbi.nlm.nih.gov/pubmed/21906355
http://dx.doi.org/10.1186/1559-0275-8-9

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