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Significance of differential expression of thymidylate synthase in normal and primary tumor tissues from patients with colorectal cancer
The role of thymidylate synthase (TS) is essential as a key rate-limiting enzyme in DNA synthesis. It is the primary target of fluorouracil and its derivates in colorectal cancer. In this study, TS mRNA expression was examined in primary tumor and normal tissues from 76 patients with high- risk stag...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170281/ https://www.ncbi.nlm.nih.gov/pubmed/21824439 http://dx.doi.org/10.1186/1756-8722-4-33 |