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Anti-MUC1 Monoclonal Antibody (C595) and Docetaxel Markedly Reduce Tumor Burden and Ascites, and Prolong Survival in an in vivo Ovarian Cancer Model

MUC1 is associated with cellular transformation and tumorigenicity and is considered as an important tumor-associated antigen (TAA) for cancer therapy. We previously reported that anti-MUC1 monoclonal antibody C595 (MAb C595) plus docetaxel (DTX) increased efficacy of DTX alone and caused cultured h...

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Detalles Bibliográficos
Autores principales: Wang, Li, Chen, Hongmin, Pourgholami, Mohammad H., Beretov, Julia, Hao, Jingli, Chao, Hongtu, Perkins, Alan C., Kearsley, John H., Li, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170300/
https://www.ncbi.nlm.nih.gov/pubmed/21931707
http://dx.doi.org/10.1371/journal.pone.0024405