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Anti-MUC1 Monoclonal Antibody (C595) and Docetaxel Markedly Reduce Tumor Burden and Ascites, and Prolong Survival in an in vivo Ovarian Cancer Model
MUC1 is associated with cellular transformation and tumorigenicity and is considered as an important tumor-associated antigen (TAA) for cancer therapy. We previously reported that anti-MUC1 monoclonal antibody C595 (MAb C595) plus docetaxel (DTX) increased efficacy of DTX alone and caused cultured h...
Autores principales: | Wang, Li, Chen, Hongmin, Pourgholami, Mohammad H., Beretov, Julia, Hao, Jingli, Chao, Hongtu, Perkins, Alan C., Kearsley, John H., Li, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170300/ https://www.ncbi.nlm.nih.gov/pubmed/21931707 http://dx.doi.org/10.1371/journal.pone.0024405 |
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