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Minimal Antizyme Peptide Fully Functioning in the Binding and Inhibition of Ornithine Decarboxylase and Antizyme Inhibitor

Antizyme (AZ) is a protein with 228 amino acid residues that regulates ornithine decarboxylase (ODC) by binding to ODC and dissociating its homodimer, thus inhibiting its enzyme activity. Antizyme inhibitor (AZI) is homologous to ODC, but has a higher affinity than ODC for AZ. In this study, we quan...

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Detalles Bibliográficos
Autores principales: Hsieh, Ju-Yi, Yang, Jung-Yen, Lin, Chih-Li, Liu, Guang-Yaw, Hung, Hui-Chih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170320/
https://www.ncbi.nlm.nih.gov/pubmed/21931692
http://dx.doi.org/10.1371/journal.pone.0024366