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Pre-Clinical Efficacy and Safety of Experimental Vaccines Based on Non-Replicating Vaccinia Vectors against Yellow Fever

BACKGROUND: Currently existing yellow fever (YF) vaccines are based on the live attenuated yellow fever virus 17D strain (YFV-17D). Although, a good safety profile was historically attributed to the 17D vaccine, serious adverse events have been reported, making the development of a safer, more moder...

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Detalles Bibliográficos
Autores principales: Schäfer, Birgit, Holzer, Georg W., Joachimsthaler, Alexandra, Coulibaly, Sogue, Schwendinger, Michael, Crowe, Brian A., Kreil, Thomas R., Barrett, P. Noel, Falkner, Falko G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170363/
https://www.ncbi.nlm.nih.gov/pubmed/21931732
http://dx.doi.org/10.1371/journal.pone.0024505