Assessing Significance in High-Throughput Experiments by Sequential Goodness of Fit and q-Value Estimation
We developed a new multiple hypothesis testing adjustment called SGoF+ implemented as a sequential goodness of fit metatest which is a modification of a previous algorithm, SGoF, taking advantage of the information of the distribution of p-values in order to fix the rejection region. The new method...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Public Library of Science
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170371/ https://www.ncbi.nlm.nih.gov/pubmed/21931819 http://dx.doi.org/10.1371/journal.pone.0024700 |