Assessing Significance in High-Throughput Experiments by Sequential Goodness of Fit and q-Value Estimation

We developed a new multiple hypothesis testing adjustment called SGoF+ implemented as a sequential goodness of fit metatest which is a modification of a previous algorithm, SGoF, taking advantage of the information of the distribution of p-values in order to fix the rejection region. The new method...

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Detalles Bibliográficos
Autores principales: Carvajal-Rodriguez, Antonio, de Uña-Alvarez, Jacobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170371/
https://www.ncbi.nlm.nih.gov/pubmed/21931819
http://dx.doi.org/10.1371/journal.pone.0024700