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Dissimilarity in the Folding of Human Cytosolic Creatine Kinase Isoenzymes

Creatine kinase (CK, EC 2.7.3.2) plays a key role in the energy homeostasis of excitable cells. The cytosolic human CK isoenzymes exist as homodimers (HMCK and HBCK) or a heterodimer (MBCK) formed by the muscle CK subunit (M) and/or brain CK subunit (B) with highly conserved three-dimensional struct...

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Detalles Bibliográficos
Autores principales: Wang, Yin, Wang, Sha, Gao, Yan-Song, Chen, Zhe, Zhou, Hai-Meng, Yan, Yong-Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170377/
https://www.ncbi.nlm.nih.gov/pubmed/21931810
http://dx.doi.org/10.1371/journal.pone.0024681