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Immunogenicity of Therapeutic Proteins: The Use of Animal Models

Immunogenicity of therapeutic proteins lowers patient well-being and drastically increases therapeutic costs. Preventing immunogenicity is an important issue to consider when developing novel therapeutic proteins and applying them in the clinic. Animal models are increasingly used to study immunogen...

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Detalles Bibliográficos
Autores principales: Brinks, Vera, Jiskoot, Wim, Schellekens, Huub
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170476/
https://www.ncbi.nlm.nih.gov/pubmed/21744171
http://dx.doi.org/10.1007/s11095-011-0523-5