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Immunogenicity of Therapeutic Proteins: The Use of Animal Models
Immunogenicity of therapeutic proteins lowers patient well-being and drastically increases therapeutic costs. Preventing immunogenicity is an important issue to consider when developing novel therapeutic proteins and applying them in the clinic. Animal models are increasingly used to study immunogen...
Autores principales: | Brinks, Vera, Jiskoot, Wim, Schellekens, Huub |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170476/ https://www.ncbi.nlm.nih.gov/pubmed/21744171 http://dx.doi.org/10.1007/s11095-011-0523-5 |
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