A randomized placebo-controlled trial of idebenone in Leber’s hereditary optic neuropathy

Major advances in understanding the pathogenesis of inherited metabolic disease caused by mitochondrial DNA mutations have yet to translate into treatments of proven efficacy. Leber’s hereditary optic neuropathy is the most common mitochondrial DNA disorder causing irreversible blindness in young ad...

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Detalles Bibliográficos
Autores principales: Klopstock, Thomas, Yu-Wai-Man, Patrick, Dimitriadis, Konstantinos, Rouleau, Jacinthe, Heck, Suzette, Bailie, Maura, Atawan, Alaa, Chattopadhyay, Sandip, Schubert, Marion, Garip, Aylin, Kernt, Marcus, Petraki, Diana, Rummey, Christian, Leinonen, Mika, Metz, Günther, Griffiths, Philip G., Meier, Thomas, Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2011
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170530/
https://www.ncbi.nlm.nih.gov/pubmed/21788663
http://dx.doi.org/10.1093/brain/awr170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170530/
https://www.ncbi.nlm.nih.gov/pubmed/21788663
http://dx.doi.org/10.1093/brain/awr170

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