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TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6
BACKGROUND: Trans-activation response element (TAR) DNA binding protein of 43kDa (TDP-43) is causally related to the neurodegenerative diseases frontotemporal dementia and amyotrophic lateral sclerosis being the hallmark protein in the disease-characteristic neuropathological lesions and via genetic...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170629/ https://www.ncbi.nlm.nih.gov/pubmed/21878116 http://dx.doi.org/10.1186/1750-1326-6-64 |