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TDP-43 knockdown impairs neurite outgrowth dependent on its target histone deacetylase 6

BACKGROUND: Trans-activation response element (TAR) DNA binding protein of 43kDa (TDP-43) is causally related to the neurodegenerative diseases frontotemporal dementia and amyotrophic lateral sclerosis being the hallmark protein in the disease-characteristic neuropathological lesions and via genetic...

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Detalles Bibliográficos
Autores principales:	Fiesel, Fabienne C, Schurr, Christine, Weber, Stephanie S, Kahle, Philipp J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170629/ https://www.ncbi.nlm.nih.gov/pubmed/21878116 http://dx.doi.org/10.1186/1750-1326-6-64

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