Cargando…

Apigenin inhibits proliferation and induces apoptosis in human multiple myeloma cells through targeting the trinity of CK2, Cdc37 and Hsp90

BACKGROUND: Multiple myeloma (MM) is a B-cell malignancy that is largely incurable and is characterized by the accumulation of malignant plasma cells in the bone marrow. Apigenin, a common flavonoid, has been reported to suppress proliferation in a wide variety of solid tumors and hematological canc...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Ming, Ma, Jian, Zhu, Hai-Yan, Zhang, Xu-Hui, Du, Zhi-Yan, Xu, Yuan-Ji, Yu, Xiao-Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170639/
https://www.ncbi.nlm.nih.gov/pubmed/21871133
http://dx.doi.org/10.1186/1476-4598-10-104