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Apoptosis Modulation as a Promising Target for Treatment of Systemic Sclerosis

Diffuse systemic sclerosis (SSc) is a fatal autoimmune disease characterized by an excessive ECM deposition inducing a loss of function of skin and internal organs. Apoptosis is a key mechanism involved in all the stages of the disease: vascular damage, immune dysfunction, and fibrosis. The purpose...

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Detalles Bibliográficos
Autores principales: Chabaud, Stéphane, Moulin, Véronique J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170778/
https://www.ncbi.nlm.nih.gov/pubmed/21912551
http://dx.doi.org/10.1155/2011/495792