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Tetraarsenic Hexoxide Induces Beclin-1-Induced Autophagic Cell Death as well as Caspase-Dependent Apoptosis in U937 Human Leukemic Cells

Tetraarsenic hexaoxide (As(4)O(6)) has been used in Korean folk remedy for the treatment of cancer since the late 1980s, and arsenic trioxide (As(2)O(3)) is currently used as a chemotherapeutic agent. However, evidence suggests that As(4)O(6)-induced cell death pathway was different from that of As(...

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Detalles Bibliográficos
Autores principales: Han, Min Ho, Lee, Won Sup, Lu, Jing Nan, Yun, Jeong Won, Kim, GonSup, Jung, Jin Myung, Kim, Gi-Young, Lee, Su-Jae, Kim, Wun-Jae, Choi, Yung Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170805/
https://www.ncbi.nlm.nih.gov/pubmed/21912568
http://dx.doi.org/10.1155/2012/201414