Methylator phenotype of malignant germ cell tumours in children identifies strong candidates for chemotherapy resistance

BACKGROUND: Yolk sac tumours (YSTs) and germinomas are the two major pure histological subtypes of germ cell tumours. To date, the role of DNA methylation in the aetiology of this class of tumour has only been analysed in adult testicular forms and with respect to only a few genes. METHODS: A bank o...

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Detalles Bibliográficos
Autores principales: Jeyapalan, J N, Noor, D A Mohamed, Lee, S-H, Tan, C L, Appleby, V A, Kilday, J P, Palmer, R D, Schwalbe, E C, Clifford, S C, Walker, D A, Murray, M J, Coleman, N, Nicholson, J C, Scotting, P J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170957/
https://www.ncbi.nlm.nih.gov/pubmed/21712824
http://dx.doi.org/10.1038/bjc.2011.218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3170957/
https://www.ncbi.nlm.nih.gov/pubmed/21712824
http://dx.doi.org/10.1038/bjc.2011.218

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