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Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion
BACKGROUND: Laminin-5 (Ln5), a heterotrimer composed of three chains (α3, β3, and γ2), is a major component of the basement membrane in most adult tissues. One of the chains, Ln5-γ2, is a marker of invasive tumours because it is frequently expressed as a monomer in malignant tumours. Recent studies...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171006/ https://www.ncbi.nlm.nih.gov/pubmed/21829200 http://dx.doi.org/10.1038/bjc.2011.283 |