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Expression of laminin 5-γ2 chain in cutaneous squamous cell carcinoma and its role in tumour invasion

BACKGROUND: Laminin-5 (Ln5), a heterotrimer composed of three chains (α3, β3, and γ2), is a major component of the basement membrane in most adult tissues. One of the chains, Ln5-γ2, is a marker of invasive tumours because it is frequently expressed as a monomer in malignant tumours. Recent studies...

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Detalles Bibliográficos
Autores principales: Hamasaki, H, Koga, K, Aoki, M, Hamasaki, M, Koshikawa, N, Seiki, M, Iwasaki, H, Nakayama, J, Nabeshima, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171006/
https://www.ncbi.nlm.nih.gov/pubmed/21829200
http://dx.doi.org/10.1038/bjc.2011.283