Differential roles of trans-phosphorylated EGFR, HER2, HER3, and RET as heterodimerisation partners of MET in lung cancer with MET amplification

BACKGROUND: MET is a receptor tyrosine kinase (RTK) whose gene is amplified in various tumour types. We investigated the roles and mechanisms of RTK heterodimerisation in lung cancer with MET amplification. METHODS: With the use of an RTK array, we identified phosphorylated RTKs in lung cancer cells...

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Detalles Bibliográficos
Autores principales: Tanizaki, J, Okamoto, I, Sakai, K, Nakagawa, K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2011
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171021/
https://www.ncbi.nlm.nih.gov/pubmed/21847121
http://dx.doi.org/10.1038/bjc.2011.322

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171021/
https://www.ncbi.nlm.nih.gov/pubmed/21847121
http://dx.doi.org/10.1038/bjc.2011.322

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