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Cytokine signals through PI-3 kinase pathway modulate Th17 cytokine production by CCR6(+) human memory T cells

Human memory T cells (T(M) cells) that produce IL-17 or IL-22 are currently defined as Th17 or Th22 cells, respectively. These T cell lineages are almost exclusively CCR6(+) and are important mediators of chronic inflammation and autoimmunity. However, little is known about the mechanisms controllin...

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Detalles Bibliográficos
Autores principales: Wan, Qi, Kozhaya, Lina, ElHed, Aimee, Ramesh, Radha, Carlson, Thaddeus J., Djuretic, Ivana M., Sundrud, Mark S., Unutmaz, Derya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171088/
https://www.ncbi.nlm.nih.gov/pubmed/21825017
http://dx.doi.org/10.1084/jem.20102516