The Paf oncogene is essential for hematopoietic stem cell function and development

Hematopoietic stem cells (HSCs) self-renew to maintain the lifelong production of all blood populations. Here, we show that the proliferating cell nuclear antigen–associated factor (Paf) is highly expressed in cycling bone marrow HSCs and plays a critical role in hematopoiesis. Mice lacking Paf exhi...

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Detalles Bibliográficos
Autores principales: Amrani, Yacine M., Gill, Jonathan, Matevossian, Armine, Alonzo, Eric S., Yang, Chingwen, Shieh, Jae-Hung, Moore, Malcolm A., Park, Christopher Y., Sant'Angelo, Derek B., Denzin, Lisa K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Brief Definitive Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171089/
https://www.ncbi.nlm.nih.gov/pubmed/21844206
http://dx.doi.org/10.1084/jem.20102170

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171089/
https://www.ncbi.nlm.nih.gov/pubmed/21844206
http://dx.doi.org/10.1084/jem.20102170

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