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Targeting cap-dependent translation blocks converging survival signals by AKT and PIM kinases in lymphoma
New anticancer drugs that target oncogenic signaling molecules have greatly improved the treatment of certain cancers. However, resistance to targeted therapeutics is a major clinical problem and the redundancy of oncogenic signaling pathways provides back-up mechanisms that allow cancer cells to es...
Autores principales: | , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171093/ https://www.ncbi.nlm.nih.gov/pubmed/21859846 http://dx.doi.org/10.1084/jem.20110846 |