Developmental timing of CCM2 loss influences cerebral cavernous malformations in mice

Cerebral cavernous malformations (CCM) are vascular malformations of the central nervous system (CNS) that lead to cerebral hemorrhages. Familial CCM occurs as an autosomal dominant condition caused by loss-of-function mutations in one of the three CCM genes. Constitutive or tissue-specific ablation...

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Detalles Bibliográficos
Autores principales: Boulday, Gwénola, Rudini, Noemi, Maddaluno, Luigi, Blécon, Anne, Arnould, Minh, Gaudric, Alain, Chapon, Françoise, Adams, Ralf H., Dejana, Elisabetta, Tournier-Lasserve, Elisabeth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171098/
https://www.ncbi.nlm.nih.gov/pubmed/21859843
http://dx.doi.org/10.1084/jem.20110571

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171098/
https://www.ncbi.nlm.nih.gov/pubmed/21859843
http://dx.doi.org/10.1084/jem.20110571

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