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A Comprehensive Metabolic Profile of Cultured Astrocytes Using Isotopic Transient Metabolic Flux Analysis and (13)C-Labeled Glucose

Metabolic models have been used to elucidate important aspects of brain metabolism in recent years. This work applies for the first time the concept of isotopic transient 13C metabolic flux analysis (MFA) to estimate intracellular fluxes in primary cultures of astrocytes. This methodology comprehens...

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Detalles Bibliográficos
Autores principales: Amaral, Ana I., Teixeira, Ana P., Håkonsen, Bjørn I., Sonnewald, Ursula, Alves, Paula M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171112/
https://www.ncbi.nlm.nih.gov/pubmed/21941478
http://dx.doi.org/10.3389/fnene.2011.00005