Epigenetic displacement of HP1 from heterochromatin by HIV-1 Vpr causes premature sister chromatid separation

Although pericentromeric heterochromatin is essential for chromosome segregation, its role in humans remains controversial. Dissecting the function of HIV-1–encoded Vpr, we unraveled important properties of heterochromatin during chromosome segregation. In Vpr-expressing cells, hRad21, hSgo1, and hM...

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Detalles Bibliográficos
Autores principales: Shimura, Mari, Toyoda, Yusuke, Iijima, Kenta, Kinomoto, Masanobu, Tokunaga, Kenzo, Yoda, Kinya, Yanagida, Mitsuhiro, Sata, Tetsutaro, Ishizaka, Yukihito
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2011
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171121/
https://www.ncbi.nlm.nih.gov/pubmed/21875947
http://dx.doi.org/10.1083/jcb.201010118

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171121/
https://www.ncbi.nlm.nih.gov/pubmed/21875947
http://dx.doi.org/10.1083/jcb.201010118

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