Cargando…

Jak2-Independent Activation of Stat3 by Intracellular Angiotensin II in Human Mesangial Cells

Ang II is shown to mediate the stimulatory effect of high glucose on TGF-b1 and extracellular matrix proteins in glomerular mesangial cells. Also inhibition of Ang II formation in cell media (extracellular) and lysates (intracellular) blocks high-glucose effects on TGF-b1 and matrix more effectively...

Descripción completa

Detalles Bibliográficos
Autor principal: Singh, Rekha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171157/
https://www.ncbi.nlm.nih.gov/pubmed/21915376
http://dx.doi.org/10.1155/2011/257862