Modeling time delay in the NFκB signaling pathway following low dose IL-1 stimulation

Stimulation of human epithelial cells with IL-1 (10 ng/ml) + UVB radiation results in sustained NFκB activation caused by continuous IKKβ phosphorylation. We have recently published a strictly reduced ordinary differential equation model elucidating the involved mechanisms. Here, we compare model ex...

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Detalles Bibliográficos
Autores principales: Witt, Johannes, Barisic, Sandra, Sawodny, Oliver, Ederer, Michael, Kulms, Dagmar, Sauter, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171178/
https://www.ncbi.nlm.nih.gov/pubmed/21910922
http://dx.doi.org/10.1186/1687-4153-2011-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171178/
https://www.ncbi.nlm.nih.gov/pubmed/21910922
http://dx.doi.org/10.1186/1687-4153-2011-3

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