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Drug therapy for hereditary cancers

Tumors arising in patients with hereditary cancer syndromes may have distinct drug sensitivity as compared to their sporadic counterparts. Breast and ovarian neoplasms from BRCA1 or BRCA2 mutation carriers are characterized by deficient homologous recombination (HR) of DNA, that makes them particula...

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Detalles Bibliográficos
Autores principales: Imyanitov, Evgeny N, Moiseyenko, Vladimir M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171323/
https://www.ncbi.nlm.nih.gov/pubmed/21819606
http://dx.doi.org/10.1186/1897-4287-9-5