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Perforin Rapidly Induces Plasma Membrane Phospholipid Flip-Flop

The cytotoxic cell granule secretory pathway is essential for host defense. This pathway is fundamentally a form of intracellular protein delivery where granule proteases (granzymes) from cytotoxic lymphocytes are thought to diffuse through barrel stave pores generated in the plasma membrane of the...

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Detalles Bibliográficos
Autores principales: Metkar, Sunil S., Wang, Baikun, Catalan, Elena, Anderluh, Gregor, Gilbert, Robert J. C., Pardo, Julian, Froelich, Christopher J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171411/
https://www.ncbi.nlm.nih.gov/pubmed/21931672
http://dx.doi.org/10.1371/journal.pone.0024286