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Perforin Rapidly Induces Plasma Membrane Phospholipid Flip-Flop
The cytotoxic cell granule secretory pathway is essential for host defense. This pathway is fundamentally a form of intracellular protein delivery where granule proteases (granzymes) from cytotoxic lymphocytes are thought to diffuse through barrel stave pores generated in the plasma membrane of the...
Autores principales: | Metkar, Sunil S., Wang, Baikun, Catalan, Elena, Anderluh, Gregor, Gilbert, Robert J. C., Pardo, Julian, Froelich, Christopher J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171411/ https://www.ncbi.nlm.nih.gov/pubmed/21931672 http://dx.doi.org/10.1371/journal.pone.0024286 |
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