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Genetic Risk Score Predicting Risk of Rheumatoid Arthritis Phenotypes and Age of Symptom Onset
BACKGROUND: Cumulative genetic profiles can help identify individuals at high-risk for developing RA. We examined the impact of 39 validated genetic risk alleles on the risk of RA phenotypes characterized by serologic and erosive status. METHODS/PRINCIPAL FINDINGS: We evaluated single nucleotide pol...
Autores principales: | Chibnik, Lori B., Keenan, Brendan T., Cui, Jing, Liao, Katherine P., Costenbader, Karen H., Plenge, Robert M., Karlson, Elizabeth W. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171415/ https://www.ncbi.nlm.nih.gov/pubmed/21931699 http://dx.doi.org/10.1371/journal.pone.0024380 |
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