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Modelling Transcriptional Regulation with a Mixture of Factor Analyzers and Variational Bayesian Expectation Maximization
Understanding the mechanisms of gene transcriptional regulation through analysis of high-throughput postgenomic data is one of the central problems of computational systems biology. Various approaches have been proposed, but most of them fail to address at least one of the following objectives: (1)...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171433/ https://www.ncbi.nlm.nih.gov/pubmed/19572011 http://dx.doi.org/10.1186/1687-4153-2009-601068 |