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Modelling Transcriptional Regulation with a Mixture of Factor Analyzers and Variational Bayesian Expectation Maximization

Understanding the mechanisms of gene transcriptional regulation through analysis of high-throughput postgenomic data is one of the central problems of computational systems biology. Various approaches have been proposed, but most of them fail to address at least one of the following objectives: (1)...

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Detalles Bibliográficos
Autores principales: Lin, Kuang, Husmeier, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171433/
https://www.ncbi.nlm.nih.gov/pubmed/19572011
http://dx.doi.org/10.1186/1687-4153-2009-601068