D-β-Hydroxybutyrate Is Protective in Mouse Models of Huntington's Disease

Abnormalities in mitochondrial function and epigenetic regulation are thought to be instrumental in Huntington's disease (HD), a fatal genetic disorder caused by an expanded polyglutamine track in the protein huntingtin. Given the lack of effective therapies for HD, we sought to assess the neur...

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Detalles Bibliográficos
Autores principales: Lim, Soyeon, Chesser, Adrianne S., Grima, Jonathan C., Rappold, Phillip M., Blum, David, Przedborski, Serge, Tieu, Kim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171454/
https://www.ncbi.nlm.nih.gov/pubmed/21931779
http://dx.doi.org/10.1371/journal.pone.0024620

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171454/
https://www.ncbi.nlm.nih.gov/pubmed/21931779
http://dx.doi.org/10.1371/journal.pone.0024620

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