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Beneficial and Detrimental Effects of Plasmin(ogen) during Infection and Sepsis in Mice
Plasmin has been proposed to be an important mediator during inflammation/infection. In this study, by using mice lacking genes for plasminogen, tissue-type plasminogen activator (tPA), and urokinase-type PA (uPA), we have investigated the functional roles of active plasmin in infection and sepsis....
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171470/ https://www.ncbi.nlm.nih.gov/pubmed/21931850 http://dx.doi.org/10.1371/journal.pone.0024774 |