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Beneficial and Detrimental Effects of Plasmin(ogen) during Infection and Sepsis in Mice

Plasmin has been proposed to be an important mediator during inflammation/infection. In this study, by using mice lacking genes for plasminogen, tissue-type plasminogen activator (tPA), and urokinase-type PA (uPA), we have investigated the functional roles of active plasmin in infection and sepsis....

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Detalles Bibliográficos
Autores principales: Guo, Yongzhi, Li, Jinan, Hagström, Elin, Ny, Tor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171470/
https://www.ncbi.nlm.nih.gov/pubmed/21931850
http://dx.doi.org/10.1371/journal.pone.0024774