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PIPKIγ Regulates Focal Adhesion Dynamics and Colon Cancer Cell Invasion

Focal adhesion assembly and disassembly are essential for cell migration and cancer invasion, but the detailed molecular mechanisms regulating these processes remain to be elucidated. Phosphatidylinositol phosphate kinase type Iγ (PIPKIγ) binds talin and is required for focal adhesion formation in E...

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Detalles Bibliográficos
Autores principales: Wu, Zhaofei, Li, Xiang, Sunkara, Manjula, Spearman, Heather, Morris, Andrew J., Huang, Cai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171478/
https://www.ncbi.nlm.nih.gov/pubmed/21931851
http://dx.doi.org/10.1371/journal.pone.0024775