Safety and Immunogenicity of an HIV Adenoviral Vector Boost after DNA Plasmid Vaccine Prime by Route of Administration: A Randomized Clinical Trial

BACKGROUND: In the development of HIV vaccines, improving immunogenicity while maintaining safety is critical. Route of administration can be an important factor. METHODOLOGY/PRINCIPAL FINDINGS: This multicenter, open-label, randomized trial, HVTN 069, compared routes of administration on safety and...

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Detalles Bibliográficos
Autores principales: Koblin, Beryl A., Casapia, Martin, Morgan, Cecilia, Qin, Li, Wang, Zhixue Maggie, Defawe, Olivier D., Baden, Lindsey, Goepfert, Paul, Tomaras, Georgia D., Montefiori, David C., McElrath, M. Juliana, Saavedra, Lilian, Lau, Chuen-Yen, Graham, Barney S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Clinical Trial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171485/
https://www.ncbi.nlm.nih.gov/pubmed/21931737
http://dx.doi.org/10.1371/journal.pone.0024517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3171485/
https://www.ncbi.nlm.nih.gov/pubmed/21931737
http://dx.doi.org/10.1371/journal.pone.0024517

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